Abbreviation: MEC;CCL28
Target Synonym: C-C Motif Chemokine 28;Mucosae-Associated Epithelial Chemokine;MEC;Protein CCK1;Small-Inducible Cytokine A28;CCL28;SCYA28
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-GST & C-His
UNIProt ID: Q9NRJ3
Background: Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.
Sequence: Ser 20-Tyr 127
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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