Recombinant Human OGA protein (His tag)

Abbreviation: OGA

Target Synonym: OGA;HEXC;KIAA0679;MEA5;MGEA5;Protein O-GlcNAcase

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: O60502

Background: Isoform 1:Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) .Does not bind acetyl-CoA and does not have histone acetyltransferase activity.Isoform 3 :Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro), but has about six times lower specific activity than isoform 1.

Sequence: Ser 6-Lys 240

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100200-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100200-20
• Package Unit: 20 µg
• Quantity Unit: STK