Abbreviation: PRRG2
Target Synonym: Transmembrane gamma-carboxyglutamic acid protein 2;PRRG2;Proline-rich gamma-carboxyglutamic acid protein 2;PRGP2;TMG2
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-GST-His
UNIProt ID: O14669
Background: The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.
Sequence: Arg 133-His 202
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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