Abbreviation: PUMA;BBC3
Target Synonym: BBC 3;Bbc3;BBC3_HUMAN;BCL 2 binding component 3;Bcl-2-binding component 3;BCL2 binding component 3;JFY 1;JFY-1;JFY1;p53 up regulated modulator of apoptosis;p53 up-regulated modulator of apoptosis;p53 Upregulated Modulator of Apoptosis;PUMA alpha;PUMA/JFY1
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: Q9BXH1
Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Activity: Immunogen(E-AB-40332)
Sequence: Met1-Asn193
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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