Abbreviation: SQSTM1;p62
Target Synonym: A170;DMRV;EBI 3 associated protein p60;EBIAP;FTDALS3;ORCA;OSF-6;OSIL;p60;P62b;PDB 3;PDB3;Sequestosome 1;SQSTM 1;STAP;STONE14;ZIP3
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: Q13501
Background: Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
Sequence: Ser 3-Lys 102
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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