Recombinant Human WNT3A protein (His tag)

Abbreviation: WNT3A

Target Synonym: Protein Wnt-3a;WNT3A

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P56704

Background: Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved cysteine-rich secreted glycoproteins important for normal developmental processes . Wnts bind to the cell surface Frizzled family receptors in conjunction with low-density lipoprotein receptor-related protein family receptors (LRP5 or 6) resulting in the stabilization of intracellular beta -catenin levels . As intracellular beta -catenin levels rise, beta -catenin binds to TCF/LEF transcription factors leading to expression of Wnt target genes.

Sequence: Ser19-Lys325

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100436-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100436-100
• Package Unit: 100 µg
• Quantity Unit: STK