Recombinant Mouse DKK1 protein (His tag)

Abbreviation: DKK1

Target Synonym: Dickkopf-related protein 1;Dickkopf-1;Dkk-1;mDkk-1;Dkk1

Target Species: Mouse

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: O54908

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning.

Sequence: Met1-His272

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDMM100011-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDMM100011-20
• Green Labware: No
• Package Unit: 20 µg
• Quantity Unit: STK