Abbreviation: Hepcidin;Hepc
Target Synonym: Hepcidin;HEPC_MOUSE;Hamp;Hamp1;Hepc;Hepc1
Target Species: Mouse
Expression Host: E.coli
Fusion Tag: N-Trx-His
UNIProt ID: Q9EQ21
Background: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.
Sequence: Asp59-Thr83
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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