Abbreviation: Tn-I
Target Synonym: Troponin I;Tnni3k;Tnni3TNNI3Tn-I
Target Species: Mouse
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: P48787
Background: Troponin I, also known as TNI and CTF1, is a 24 kDa component of a protein complex on striated muscle thin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins C and T. The expression of cardiac Troponin I (TNNI3) is restricted to cardiac muscle, while TNNI1 and TNNI2 (encoded by distinct genes) are expressed in skeletal muscle. Mutations of cardiac Troponin I are associated with hereditary cardiomyopathy.
Sequence: Met 1-Gly 211
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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