Abbreviation: CD146;MCAM
Target Synonym: Cell surface glycoprotein MUC18;MUC18;Mcam;Gicerin;Melanoma cell adhesion molecule;Melanoma-associated antigen MUC18;CD146
Target Species: Rat
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: Q9EPF2
Background: Melanomia Cell Adhesion Molecule (MCAM), also known as CD146 and MUC18, is a putative Ig-superfamily adhesion molecule that is expressed on endothelial cells and a variety of tumor cells. MCAM is associated with tumor progression and metastasis and may be involved in embryonic neural development. An alternately spliced isoform of rat MCAM has a 40 residue deletion in the cytoplasmic domain.
Sequence: His 151-Val 350
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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