Abbreviation: GPRC6A
Target Synonym: bA86F4.3;G protein coupled receptor 33;G-protein coupled receptor family C group 6 member A;GPC6A;GPCR33;Predicted with SOSUI analysis;seven transmembrane helix receptor
Target Species: Rat
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: Q70VB1
Background: Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritionnal and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids.
Sequence: Thr 456-Asp 590
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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