Abbreviation: KLK6
Target Synonym: Bssp;hK 6;hK6;Kallikrein 6 precursor;Kallikrein related peptidase 6;Kallikrein-6;Kallikrein6;KLK 6;Klk7;KLK9;Klk29;Klk6;KLK6;Klk7;KLK9;MGC9355;mGK 1;mGK1;MSP;Neurosin;Protease M;Protease serine 18;Protease serine 9;PRSS 18;PRSS 9;PRSS18;PRSS9;Serine protease 18;Serine protease 9;SP 59;SP59;Tissue kallikrein;TK
Target Species: Rat
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: P36374
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Sequence: Ile25-Pro261
Purity: > 80 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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