Abbreviation: NT-proBNP
Target Synonym: Natriuretic peptides B;ANFB_RAT;Nppb;Brain natriuretic factor prohormone;preproBNP;proBNP;Gamma-brain natriuretic peptide;Iso-ANP;
Target Species: Rat
Expression Host: E.coli
Fusion Tag: N-GST
UNIProt ID: P13205
Background: Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Likely involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, kaluresis and chloruresis
Sequence: His27-Arg76
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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