Product Description: Reversine is a novel class of ATP-competitive Aurora kinase inhibitors. Reversine inhibits the phosphorylation of histone H3, a direct downstream target of Aurora kinases. It acts as a selective A3 adenosine receptor antagonist. Reversine functions as a dual inhibitor of MEK1 and nonmuscle myosin II heavy chain. It also acts as an ATP-competitive, reversible and selective inhibitor of ARK-1, ARK-2, and ARK-3.
CAS Number: 656820-32-5
Molecular Weight: 393.49
Structure: C21H27N7O
Compound Purity: >98%