Application Note: Procalcitonin Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-Procalcitonin in immunological assays.
General Disclaimer Note: This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Other Performance Data: Endotoxin Level: Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein. Biologic Activity: Activity is tested using Biomerieux reagents on the Min-Vidas at 80 ng/mL, with a typical recovery of 80%.
Physical State: Lyophilized
Purity and Specificity: Procalcitonin purity was determined to be greater than 97% as determined by HpLC and by reducing and non-reducing SDS-pAGE.
Background: Procalcitonin is a precursor of the peptide hormone called calcitonin. Procalcitonin is mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin have been shown to rise significantly after bacterial infection, trauma or shock. Recombinant human Procalcitonin is a non-glycosylated protein, containing 116 amino acids, with a molecular weight of 12.8 kDa.
Low Endotoxin: Yes
Other: User Optimized
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