Application Note: Exodus-2 Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Exodus-2 in immunological assays.
Concentration Value: 0.1 mg/ml
General Disclaimer Note: This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Other Performance Data: Endotoxin Level: Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein. Biologic Activity: The activity is determined by its ability to chemoattract 5-10 day old cultures of human peripheral blood lymphocytes at concentrations between 200 ng/mL- 600 ng/mL.
Physical State: Lyophilized
Purity and Specificity: Exodus-2 / CCL21 purity was determined to be greater than 98% as determined by analysis by SDS-pAGE.
Background: Exodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% amino acid identity. Recombinant mouse Exodus-2 is a non-glycosylated protein, containing 110 amino acids, with a molecular weight of 12 kDa.
Low Endotoxin: Yes
Other: User Optimized
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