Conjugation: HRP: Horseradish Peroxidase
Description of Target: RPS6KA2 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RPS6KA2
Key Reference: Wissing,J., (2007) Mol. Cell Proteomics 6 (3), 537-547
Molecular Weight: 81kDa
Peptide Sequence: Synthetic peptide located within the following region:
LSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTSTRProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Ribosomal protein S6 kinase alpha-2
Protein Size: 733
Purification: Affinity Purified
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