Application Note: WB: 1:1000-1:2000. ICC/IF: 1:100-1:1000. IP: 1:300-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 45
Form: Liquid
Buffer (with preservative): Filter-sterilized PBS, 50% Glycerol, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009]
Uniprot ID: P31350
Antigen Species: Human
Immunogen: Synthetic peptide (11 amino acids) in the C-terminal region of human and mouse RRM2, conjugated with KLH
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: ribonucleotide reductase regulatory subunit M2