SB-4, CAS 100874-08-6

Formulation: A solid

Formal Name: 2-[[(4-bromophenyl)methyl]thio]-benzoxazole

Purity: ≥98%

Formula Markup: C14H10BrNOS

Formula Weight: 320,2

Shelf life (days): 1460

CAS Number: 100874-08-6

Notes: SB-4 is an activator of bone morphogenetic protein 4 (BMP4) signaling.{51511} It induces BMP4 signaling in a reporter assay using HEK293 cells expressing a recombinant human BMP4 response element (EC50 = 74 nM). SB-4 (10 µM) increases phosphorylation of SMAD1, -5, and -9 in HEK293 cells. It also induces Blimp1 and Tfap2c expression, markers of germline differentiation, in mouse embryonic stem cells.{51510}

• SKU: CAY37748-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37748-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK