SB431542 , CAS 301836-41-9

Product Description: SB431542 is a potent and selective inhibitor of the TGF-β superfamily type 1 (TGF-β 1) activin receptor-like kinase (ALK5) receptors, and its relatives ALK4 and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6. SB431542 inhibits the TGF-β-mediated activation of SMAD proteins, expression of collagen and fibronectin, cell proliferation and cell motility. It does not inhibit kinases that are activated in response to serum or stress such as ERK, p38 or JNK.

CAS Number: 301836-41-9

Molecular Weight: 384.39

Structure: C22H16N4O3

Compound Purity: >99%

• SKU: CGSSM33-2
• Manufacturer: Cell Guidance Systems
• Manufacturer SKU: SM33-2
• Package Unit: 2 mg
• Quantity Unit: STK