Abbreviation: SEC61B
Target Synonym: SEC61B; Sec61 translocon beta subunit
Conjugation: Unconjugated
UNIProt ID: P60468
Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human SEC61B
Dilution: WB 1:500-1:2000,IF 1:50-1:200