Application Note: Anti-SET9 Antibody has been tested by Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 50 kDa in the appropriate cell lysate or extract.
Concentration Value: neat
Western Blot Dilution: 1:1,000
General Disclaimer Note: This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen: Anti-SET9 Antibody was produced in rabbits by repeated immunizations with a recombinant protein of human Set9.
Physical State: Liquid (sterile filtered)
Purity and Specificity: Anti-Set9 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with Set8 from species other than human not tested.
Background: Set9 is a histone methyltransferase which specifically methylates lysine 4 of histone H3 being a specific tag for epigenetic transcriptional activation. Further, methylation of histone H3K4 by Set9 precludes deacetylation of H3 by the NuRD complex and impairs Suv39h1-mediated methylation of H3K9. Set9 also methylates the tumor suppressor p53 at lysine 372, thereby enhancing its stability. IT contains a SET domain but lacks the pre- and post-SET domains. Anti-Set9 Antibody is ideal for research in Epigenetics, Gene Expression and Chromatin Remodeling.
Low Endotoxin: No
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