SETD2 Polyclonal Antibody, Rabbit

Abbreviation: SETD2

Target Synonym: SETD2;HBP231;HIF-1;HIP-1;HSPC069;HYPB;KMT3A;LLS;SET2;p231HBP

Conjugation: Unconjugated

UNIProt ID: Q9BYW2

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human SETD2

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-93066-200
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-93066-200
• Green Labware: No
• Package Unit: 200 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit