Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SH3BP2
Key Reference: Idowu,B.D., (2008) Br J Oral Maxillofac Surg 46 (3), 229-230
Molecular Weight: 62kDa
Peptide Sequence: Synthetic peptide located within the following region:
RQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: SH3 domain-binding protein 2
Protein Size: 561
Purification: Affinity Purified
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