Background: Exalphas' rat and human SAP kinase detects native SAP kinase by immunoprecipitation in rat and human (HeLa) cells. SAP kinase is induced by stress agonists such as UV irradiation, heat shock and inflammatory cytokines. These stress stimuli result in the phosphorylation of and enzymatic activation of Stress Activated Protein Kinases (SAP kinases). Three SAP kinase gene are known to exist, , and , which are differentially spliced giving 10 gene products in total.
Immunogen: Full length SAP Kinase protein.
Purification Method: Ammonium Sulfate Precipitation.
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.
UniProt: Q9BP27.
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.