Clone Name: SD20-75
Application Note: WB: 1:1000-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 68
Form: Liquid
Buffer (with preservative): 1x TBS (pH7.4), 1% BSA, 40% Glycerol, 0.05% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
Uniprot ID: Q06124
Antigen Species: Human
Immunogen: Recombinant protein
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: protein tyrosine phosphatase non-receptor type 11
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