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Applications: Useful for studying protein binding and screening small molecular inhibitors
Description: Signal regulatory proteingamma (SIRP-γ), also known as signal regulatory protein beta 2, and CD172g, GenBank Accession No. NP_018556, a.a. 29-360, fused at the C-terminus to the Fc portion of human IgG1 and Cterminal Avitag™, MW 67.6 kDa, expressed in a HEK293 expression system and enzymatically biotinylated using Avitag™ technology. Note: SIRP-γ is heavily glycosylated, resulting in higher molecular weight. Biotinylation was confirmed to be >90%.
Format: Aqueous buffer solution
Formulation: 8 mM Phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20%glycerol
Genbank: NP_018556
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion, C-terminal Avi-tag™
Uniprot: Q9P1W8
Warnings: Avoid freeze-thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Barclay, AN and Brown, MH., Nature Rev. Immunol. 2006; 6: 457-464.