SLC7A11/xCT Polyclonal Antibody, Rabbit

Abbreviation: SLC7A11/xCT

Target Synonym: SLC7A11;CCBR1;xCT

Conjugation: Unconjugated

UNIProt ID: Q9UPY5

Background: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human SLC7A11/xCT

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-93104-60
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-93104-60
• Green Labware: No
• Package Unit: 60 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit