SP600125, CAS 129-56-6

Product Description: SP600125 is a potent, selective and reversible inhibitor of the three JNK enzymes (c-Jun N-terminal kinases). Inhibition is competitive with respect to ATP, and over 300-fold more selective for JNK as compared to ERK1 and p38-2 MAP kinases. SP600125 was shown to cause a dose-dependent inhibition of the phosphorylation of c-Jun, and thereby the expression of inflammatory genes COX-2, IFN-gamma, IL-2 and TNF-alpha.

CAS Number: 129-56-6

Molecular Weight: 220.23

Structure: C14H8N2O

Compound Purity: >99%

• SKU: CGSSM41-100
• Manufacturer: Cell Guidance Systems
• Manufacturer SKU: SM41-100
• Package Unit: 100 mg
• Quantity Unit: STK