Abbreviation: SSCA1/SerpinB3
Target Synonym: SERPINB3;HsT1196;SCC;SCCA-1;SCCA-PD;SCCA1;SSCA1;T4-A;serpin B3
Conjugation: Unconjugated
UNIProt ID: P29508
Background: Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human SSCA1/SerpinB3
Dilution: WB 1:500-1:2000,IF 1:50-1:200