Abbreviation: STAT4
Target Synonym: STAT4;SLEB11
Conjugation: Unconjugated
UNIProt ID: Q14765
Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human STAT4
Dilution: WB 1:500-1:2000,IHC 1:50-1:200
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