Description: Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated polypeptide chain containing 165 amino acids. The ED50 is determined by the dose-dependant stimulation of the proliferation of human MO7e cells which is < 10 ng/ml.