Clone Name: EP201
Application Note: IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 32
Positive Control: Plasmacytoma, Tonsil
Form: Liquid
Buffer (with preservative): 10mM PBS pH7.5, 1% BSA, 0.05% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]
Uniprot ID: P18827
Antigen Species: Human
Immunogen: A synthetic peptide corresponding to residues in human CD138 protein
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: syndecan 1
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