Tat-CIRP (trifluoroacetate salt)

Formulation: A solid

Purity: ≥95%

Formula Markup: C123H206N56O33 • XCF3COOH

Formula Weight: 2997,3

Shelf life (days): 1460

Notes: Tat-CIRP is a peptide inhibitor of the protein-protein interaction between myeloid differentiation 2 (MD-2), also known as lymphocyte antigen 96 (LY96), and cold-inducible RNA binding protein (CIRP).{68525} It binds to MD-2 and disrupts the interaction between MD-2 and CIRP in co-immunoprecipitation assays. In vivo, Tat-CIRP (10 and 20 mg/kg) reduces infarct volume in a mouse model of stroke induced by middle cerebral artery occlusion (MCAO). It also reduces infarct volume and decreases the time to pick up and withdraw food with the stroke-affected arm in a rhesus monkey model of thrombosis-induced stroke.

• SKU: CAY37446-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37446-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK