Target: Tau (pThr217)
Conjugate: APC
Product Type: Monoclonal
Clone Number: 15B7
Immunogen: Synthetic peptide of Wild-type Human Tau (pThr217) AA 210-224: SRTPSLP-pT-PPTREPK
Swiss-Prot: P10636
Purification: Protein G Purified
Storage Buffer: 95.64mM Phosphate, 2.48mM MES and 2mM EDTA
Concentration: 1mg/ml
Specificity: Detects phosphorylation on Thr217
Cellular Localization: Intracellular / Secreted
Tissue Specificity: Brain / Skeletal Muscle
Scientific Background: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.