TCO-PEG4-VC-PAB-MMAE, CAS 2758671-45-1

Product Description: TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162)[1]. TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

Applications: Cancer-programmed cell death

Formula: C78H127N11O19

References: [1]Yang Yi, et al. Preparation of site-specific antibody conjugates. Patent WO2022037665.

CAS Number: 2758671-45-1

Molecular Weight: 1522.91

Compound Purity: 99.30

Research Area: Cancer

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-148057-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-148057-1
• Package Unit: 1mg
• Quantity Unit: STK