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Description: Human Transforming growth factor beta receptor I (TGFβR1), also known as activin A receptor type II-like kinase, AAT5 and LDS1, GenBank Accession No. NM_004612.4, a.a 34-126, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag, expressed in a HEK293 cell expression system and enzymatically biotinylated using Avi-tag™ technology. Biotinylation is confirmed to be ≥90%. MW=39 kDa. This protein runs at a higher molecular weight due to glycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_004612.4
Storage Stability: At least 6 months at -80°C.
Supplied As: Aqueous buffer solution.
Uniprot: P37173
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Loeys, B.L., et al., Nature Genetics. 2005; 37: 275-281.
2. Singh, K.K., et al., Human Mutation. 2006; 27(8): 770-777.
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