Application Note: WB: 0.25-0.5μg/ml. ICC/IF: 5μg/ml. IHC-P: 2-5μg/ml. FACS: 1-3μg/1x10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 134
Form: Liquid
Buffer (with preservative): 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, no preservative.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Uniprot ID: Q9UDY2
Antigen Species: Human
Immunogen: A synthetic peptide corresponding to a sequence of human TJP2/ZO2 (QEAQNARIEIAQKHPDIYAVPIK).
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: tight junction protein 2
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