TSN Polyclonal Antibody, Rabbit

Abbreviation: TSN

Target Synonym: BCLF-1;C3PO;RCHF1;REHF-1;TBRBP;TRSLN;TSN;translin

Conjugation: Unconjugated

UNIProt ID: Q15631

Background: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human TSN

Dilution: WB 1:500-1:2000,IHC 1:50-1:200

• SKU: ELSE-AB-92099-200
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92099-200
• Green Labware: No
• Package Unit: 200 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Western Blotting, Immunohistochemistry
• Isotype: IgG
• Host: Rabbit