Tumor Necrosis Factor Receptor Type 2, human recombinant (rhuTNFBR)

Kategorie: Cytokines

Storage: -20°C

Weight: 20 kD

Purity: >97%

Description: Protein function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. [The UniProt Consortium]

• SKU: BOL99932.1
• Manufacturer: Biomol
• Manufacturer SKU: 99932.1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Human Gene ID: 7133
• Host: Escherichia Coli