YB-1/YBX1 Polyclonal Antibody, Rabbit

Abbreviation: YB-1/YBX1

Target Synonym: YBX1;BP-8;CBF-A;CSDA2;CSDB;DBPB;EFI-A;MDR-NF1;NSEP-1;NSEP1;YB-1;YB1

Conjugation: Unconjugated

UNIProt ID: P67809

Background: This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human YB-1/YBX1

Dilution: WB 1:500-1:1000

• SKU: ELSE-AB-92743-120
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92743-120
• Green Labware: No
• Package Unit: 120 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit