Product Type: Antagonist
CAS No.: 39025-23-5
MolecularFormula: C21H28O2
Molecular Weight: 312,5
Source: Synthetic
Purity: >98% (TLC); NMR (Conforms)
Solubility: May be dissolved in DMSO (6 mg/ml, warm); or Ethanol (3 mg/ml, warm)
Appearance: Off-white powder
PubChem CID: 6450278
Scientific Background: Z-Guggulsterine acts as a selective antagonist at farnesoid X receptors, and inhibits FXR transactivation. It is also a retinoic acid receptor (RAR) pathway inhibitor. Attenuates astrocyte-mediated neuroinflammation by inhibiting toll-like receptor 4 pathway.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.