115-7C

Hsp70 Activator

Product Type: Activator

MolecularFormula: C23H22Cl2N2O5

Molecular Weight: 477,34

Source: Synthetic

Purity: >98%

Solubility: Soluble in DMSO (20 mg/ml)

Appearance: White solid

Scientific Background: 115-7c activates Hsp70 ATPase turnover rate and promotes Hsp70 substrate refolding. It binds to the IIA subdomain of DnaK and promotes the DnaK-DnaJ complex. Equivalent with SW02.

References: 1. Wisen et al., (2010) ACS Chem. Biol., 5: 611-622. 2. Jinwal et al. (2009) J.Neurosci. 29:12079. 3. Chafekar et al. (2012) ACS Chem Biol. 7:1556. 4. Walter et al. (2011) J. Biol. Chem. 286:40486

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-123-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-123-5MG
• Package Unit: 5 mg
• Quantity Unit: STK
• Reactivity: Various species