Formulation: A solution in ethanol
Formal Name: 15,19,28-tris(2-hydroxytetradecyl)-15,19,24,28-tetraazadotetracontane-13,30-diol
Purity: ≥95%
Formula Markup: C80H166N4O5
Formula Weight: 1264,2
Shelf life (days): 1095
Notes: 1O14 is an ionizable cationic lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs).{65537} 1O14-containing LNPs have been used for the delivery of IL-1β siRNA to induce gene silencing and hepatoprotective effects in a mouse model of acute liver injury induced by LPS and galactosamine (GalN).