Formulation: A solid
Formal Name: cyclic 2′,3′-(hydrogen phosphate) adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt, disodium salt
Purity: ≥95%
Formula Markup: C21H24N7O16P3 • 2Na
Formula Weight: 769,4
Shelf life (days): 730
CAS Number: 100929-77-9
Notes: 2',3'-cyclic NADP+ is a substrate for 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNP), an enzyme that is abundant in myelin.{67326,67327} It has been used in coupled enzyme assays to quantify CNP activity.{67326} 2',3'-cyclic NADP+ (5 µM) increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria.{67327}