Formulation: A solution in water
Formal Name: ((2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate
Purity: ≥95%
Formula Markup: C10H13N2O13P3 • 4Na
Formula Weight: 554,1
Shelf life (days): 730
Notes: 2',3'-Dideoxythymidine-5'-O-triphosphate (ddTTP) is a reverse transcriptase inhibitor (Kis = 40 and 25 nM for the visna virus and HIV-1 enzymes, respectively).{28268,28264} It also inhibits DNA polymerase γ (Ki = 400 nM for the bovine enzyme).{49781} ddTTP has been used to terminate chain extension produced by the Taq polymerase in PCR assays.{28266}