Formulation: A solid
Formal Name: 4-amino-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone
Purity: ≥98%
Formula Markup: C9H12FN3O4
Formula Weight: 245,2
Shelf life (days): 1460
CAS Number: 56632-83-8
Notes: 2'-Fluoro-2'-deoxy-arabino-cytidine is a fluorinated derivative of the deoxyribonucleoside 2'-deoxycytidine (Item Nos. 34708 / 30125).{67675} It is cytotoxic to CCRF-HSB-2 T lymphoblast, COLO 320DM colon, and MKN28 gastric cancer cells (IC50s = 0.15, 0.19, and 29 µg/ml, respectively). 2'-Fluoro-2'-deoxy-arabino-cytidine inhibits HIV-1 replication in HIV-1-infected C8166 cells (IC50 = 0.7 µM), as well as herpes simplex virus 1 (HSV-1) and HSV-2 replication in HSV-1- or HSV-2-infected Vero cells (IC50s = 0.12 and 0.3 µM, respectively).{67676,67677}