3-Acetylaconitine, CAS 77181-26-1

3-Acetylaconitine, CAS 77181-26-1
SKU
CAY36155-5
Packaging Unit
5 mg
Manufacturer
Cayman Chemical

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Formulation: A solid

Formal Name: 20-ethyl-1α,6α,16β-trimethoxy-4-(methoxymethyl)-aconitane-3α,8,13,14α,15α-pentol, 3,8-diacetate 14-benzoate

Purity: ≥95%

Formula Markup: C36H49NO12

Formula Weight: 687,8

Shelf life (days): 1460

CAS Number: 77181-26-1

Notes: 3-Acetylaconitine is a diterpene alkaloid that has been found in Aconitum and has diverse biological activities.{62673,62674} It is cytotoxic to P388 leukemia cells (IC50 = 18.6 µM).{62673} It inhibits brevetoxin binding to (IC50 = 1.3 µM), and increases free sodium and calcium concentrations in, rat brain synaptosomes. 3-Acetylaconitine (60-100 nM) induces arrhythmia in isolated guinea pig atria.{62674} In vivo, 3-acetylaconitine (100 µg/kg, i.v.) reduces paw licking, flicking, and shaking in a mouse model of formalin-induced inflammatory pain.
More Information
SKU CAY36155-5
Manufacturer Cayman Chemical
Manufacturer SKU 36155-5
Green Labware No
Package Unit 5 mg
Quantity Unit STK
Application Reinstoffe
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