Formulation: A solid
Formal Name: 2-chloro-6-(hydroxymethyl)-1,4-benzenediol
Purity: ≥98%
Formula Markup: C7H7ClO3
Formula Weight: 174,6
Shelf life (days): 1460
CAS Number: 32744-80-2
Notes: 3-Chlorogentisyl alcohol is a phenol and microbial metabolite that has been found in Ampelomyces and has diverse biological activities.{68706,68707,68708} It scavenges DPPH (Item No. 14805) radicals in a cell-free assay (IC50 = 1 µM).{68707} 3-Chlorogentisyl alcohol is active against methicillin-resistant S. aureus (MRSA; MIC = 50 µg/ml), as well as 13 Gram-positive and Gram-negative bacteria when used at a concentration of 50 µg/disc.{68707,68706} 3-Chlorogentisyl alcohol has concentration-dependent antifouling activity against barnacle (B. amphitrite) cyprids in the conventional submerged assay using polystyrene plates. It induces apoptosis and cell cycle arrest at the S phase in HeLa cervical cancer cells when used at a concentration of 50 µM.{68708} 3-Chlorogentisyl alcohol (35 µM) induces ssDNA breaks in a comet assay using HeLa cells.
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