Product Description: 4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. LOX-1 isshort for Lectin-like oxidized low-density lipoprotein receptor-1.
Formula: C15H10O4
References: [1]Ribeiro D, et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. Eur J Med Chem. 2014 Jan 24;72:137-45./[2]Proença C, et al. α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1216-1228.
CAS Number: 6665-67-4
Molecular Weight: 254.24
Compound Purity: 99.95
Research Area: Others
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Glycosidase;Lipoxygenase